Hmmm, I'm running just about the same system you are but with a couple of exceptions (256 megs ram, Memorex CD-rom, ATI Rage Pro Fury) and I haven't had any problems.
One thing I have learned from visiting various places for games I play is to make sure I delete temp files, empty cache, and DEFRAG on a regular basis. I also noticed this recommended in the read-me file for DarkStone if I remember correctly. IF you don't already do regular maintenance it's an excellent idea. I've known of quite a few folks who've installed a game and then have it not run at all when that was the only problem.
I hope this helps, and if not hopefully someone with a better idea will come along soon.
Edited because I can't read or type or proof-read.
[This message has been edited by Regina (edited 05-12-2001).]