Well, you are quite far in the game when it comes to restarting it, but then again, sometimes the fun is in it as well
There were really just 1-2 items in the city which were good to use, but nothing too crucial really. I used to think earlier also that especially one thing there would be the absolute must, but come to think of it, it's good but not a "must". So you can just freely move on and do the
fishland on the other round
Well OK, you will miss the Saemon's good excuse line:
"Oh hell. I will be below the deck, securing the... ah... something"