The persusion and seduction skill will definitely gain you some extra XP through conversation, and some intimate moments with VV an Jeanette.
But it won't help you overcome a bunch wild vampires who are trying to bite your head off. I always played as a Brujah, a little bit of everything. Besides, ever since "Redemtion" i'm used to being a Brujah.
I guess the patch fixed most bugs in the game, the Dr. Johansson bug being the worst of em all, but didn't fix the memory leakage, hence the lag when you run around outside. But like you, i could also live with that.
Yeah, i still play it.