[Kaleban]

Sometimes the game gets stuck in a certain "mode..."

For example:
An NPC approaches you to initiate dialogue.
You just killed some enemies.

The game will not let you save or leave the area, as a scripted sequence has begun which must be completed. For the most part, moving your PC around a bit will break the "script loop" and allow you to continue as normal. On slower processors/less memory/outdated equipment/bad BO/ this is a problem as the resources get tied up by the script. Just be patient.