The vampire maddig is in the subdungeon. It is off a room you get to by going up the ramp in the room with whirling blades. She is obvious when you explore the subdungeon. You open her door with the Lich's staff.
The vampire adrianna is at the end of one of the underwater tunnels you swim through after turning right at the stairs that lead down to the Lich. For full play of the game you should accept her quest before going after maddig.
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