If SOU and/or HOTU are not 1.66, they will have to be patched too, and I think separately.
Since you have NWN 1.66, I'm surprised it's asking for a CD. Definitely, go over to the Bioware forums, sign up, register your NWN CD, and ask in the tech forum for help. Only registered owners can post in the tech forum, and they don't allow tech questions in the general discussion area.
Nightowl2
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