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Nishruus should only "eat" items that have charges and do not recharge each day - wands usually. Each time they hit you they remove random spells from your inventory and drain charges from your wands or other charge-limited items, if an item is drained below 1 charges it disappears. They should never eat non charge-limited items. However in a standard installation of BG2 (even with the official patch) many other items can be eaten by Nishruu, including many quest items and artifact pieces.
The BG2 Fix Pack on the "Baldurdash" website certainly fixes this problem, I don't know whether ToB does.
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