Don't be afraid to take some of the NPC combinations that cause conflicts.
In general this means having x-good and x-evil NPCs in your party together. The neutral aligned characters tend to get along with everyone (or at least tolerate them)
Most people will tell you to avoid certain NPC pairs, because they hate each other, but that in itself can add to the game. Some of the combos in this catagory are Keldorn/Viconia, Edwin/Minsc, Korgan/Aerie?, Haer Dalis--Aerie--Yourself if you are romancing Aerie
It can also be fun to take all three female romance options at the start. They can get pretty hostile to each other if you are in the beginning romance stages with all of them.
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"Many are my names in many countries. Mithrandir among the Elves, Tharkun to the Dwarves; Olorin I was in my youth in the West that is forgotten, in the South Incanus, in the North Gandalf; to the East I go not"
--The Two Towers
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