As I remember it I used the "recommended install" and neither did I have TotSC installed nor did I have any patches (which is the same way I have it now)..
We have two CD-drives D:\ and E:\
By "cache" I guess you mean the "temp" folder? If I empty it, the assertion-error goes away and I may load BG again. Only to come back after I have failed loading my "inserted" save-files..
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