You can always delete everything in the TEMP folder, it's just files that the computer has used temporarly, if it is still needed then it is in use and can't be deleted... so wipe them out... all of them
And here is an old DOS trick if you want to avoid the files stacking up then add this to you Autoexec.bat
rm ------------
del *.* c:\windows\temp /y
deltree * c:\windows\temp /y
rm ------------
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