LOL I still get lost unless I look at the map while flying. Flying is the best way IMO not to get lost. Also, just remember at least two cantons AND on what side their on, ie, left or right, north or south. Ooh Ooh! Almost forgot. If you have a very high Acrobatics skills, its soooo fun to try and jump from one canton to the next. Just make sure to have a constant restore health item.
or just cast levitate if you think you're not gonna make it.