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It won't work: the drain is instant. Unless maybe you equip the thing and BEFORE closing the inventory, you quaff loads of health potions. It might make you recover health so fast that you regain enough hit points to counter the curse in only one frame (the time it takes for the game to determine the fact that you have 0 hit points and you must die). It might work, it might not. Most probably not. Get those fortify health potions.
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Never attribute to malice that which can be ascribed to sheer stupidity
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