[Raktizz Nemmex]

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Here is a list of everyone who gives you quests
Ajira (Balmora), Ranis(Balmora), Edwinna(Ald-ruhn), Skink(Sadrith-Mora), and finally Trebonius.
You don't have to Trebonius's quests, but they do raise your reputation quite a bit. And for Skink, when he says he is making a potion for Edwinna or whatever, all you need to do is wait a while then go back and ask him.
But if you've done all the quests in Balmora, and Ald-ruhn and a few for Skink, you will be high enough to challenge Trebonius, and if you have a good weapon, it shouldn't be too hard to kill him

Raktizz