If you are combat oriented character, after level 25+ things are going to get quite easy. I am currently at level 59, half of my stats are at 100 where as the others are in the 70s and 80s. I cleaned out the Dagon Ur's lair without even using a single potion of healing. Actually, to be honest I haven't been using any potions since level 23.
IMHO, enchant skill is one of the most useful skill in the game.