Spoiler Alert
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1. Forget about the blocked tunnel, it has nothing to do with the quest and BTW, I read somewhere that it is empty anyway.
2. Bug? Maybe. Just before you kill the high priest, he should talk to you. Exhaust all the topics and before you kill him. Just before he died, he will put a curse on you and you will be inflicted with corpus disease; which triggers the next quest - to find the cure. If you happened to kill him before he can initiate conversation, you will miss the trigger and the quest can not be completed.
Or maybe you overlooked and did not kill him. Try to go back to the place and give a thorough search. Make sure you kill everyone there. If you have killed him before he has the chance to initiate conversation, you will have to reload you old savegame before entering the cave.
3. If you have killed him and you do not have a savegame, use the console command to respawn him. This time, make sure that you only kill him AFTER he has the chance to initiate conversation.
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