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Personally, I think any Paladin subclass is very well equipped for soloing. They're good fighters, they rock once they get their hands on Carsomyr. They have some good spells available, they can heal a good amount of HP quickly with Lay On Hands.
Monks are good too, good innate Magic Resistance, can Lay On Hands too, although for a lesser amount of HP than Paladins. Nice special abilities, quick movement makes running away easier if you ever have to resort to that. Immune to poison and disease, Charm/Domination etc.
Barbarians and Berserkers also pack a punch, with all the bonuses and immunities they get while enraged. I've heard good things about Archers too, but haven't tried that out myself. Any of the three mentioned here would make a good solo class.
My advice is: just go with what you like and try to come up with strategies and tricks as you go along, this will make the game lots of fun and very satisfying if you succeed.
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