I already had the wardstone from Perth, so I went and killed Desharik and then walked to the Asylum.
I decided to play through last night and you'll be pleased to know that Desharik shows up later anyway after you've stolen his horn, permitting the game to go on.
This means, by the way, that you get the EXP for killing him twice if you do it my way.
Thanks for the replies!
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