Ehhhh... ...
When I'm high-level enough, Greater Malison followed by Horrid Wilting.
If I'm fighting against non-undead Humanoids, Emotion after the Greater Malison.
I use Spell Sequencer for tough enemies, usually contains Flame Arrow, Polymorph and one other random attack spell.
I will always favour Chromatic Orb over Magic Missile, except during the phase when my Sorcerer is Lvl 10-12, because I do not like the petrify effect. In my opinion, anything that can kill a Mind Flayer in one hit, is a damn good spell and Chromatic Orb can do that.
I put Mirror Image and Blur for Minor Spell Sequencer.
I put Spell Shield, Spell Immunity and Protection from Magical Energy in my Spell Trigger.
I put Dispel Magic in my Contingency, condition when I am helpless.
Favourite spell though, is Finger of Death, followed by Chromatic Orb.
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If not a Sorcerer, then a Paladin.