Wohoo! I did it, I beat the twisted rune losers with only my multi classed Half-ELf (fighter/mage/thief). It took me an hour of play to find a way of killing them. Heres how I did it: I made shangalar appear on the table in the centre and ran out of his view before he said anything. I then cast 2 fog of death spells to get him down to near death. Then I cast 7th level spell turning and run out so he would speak to me. As soon as he teleported near the entrance I hit him with the ring of the ram and he panicked and run off and got killed in the fog of death that was still active. As I hit shangalar with the ring of the ram his beholder friend was casting away, no problem his spells came right back at him
He ended up being petrified by his own spell (Haha!). Luckily his eye survived so I could get of there! It didnt take much more to kill the other 3 but that vampire was a little tough (stupid level drain....)