A.I can end up with your cahracters going all over the place and attacking things you dont't want to just because the circle is red (e.g., TSOTSC sparring dummies). Best to keep it off and set the Auto-Pause functions to help manage. (I prefer doing this anyway - given the crap monster AI, would you really trust the PC with your characters?)
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In the kingdom of the blind, the one-eyed man is pimp.
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