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As Vaskez says, do not use any area effect spell, because they can make her turn on you, and depending on who is in your party change your tactics accordingly:
Warriors= surround all of your weaker units with the warriors and leave your strongest out where the Illithids/Ulithids/Mind Flayers appear. Then work your way out.
Spellcasters= leave the spell caster outside the spawning point of the creatures and summon creatures between your party and the creatures. Then cast spells on them.
Personally I have mostly warriors with 1/2 propper spell casters and do as many quests as I can before I go off on the main quest so that I these difficult parts are a breeze. Then I would go and finish off the quest I couldn't before I went on the main quest and get the really good equipment for the final battles and Throne of Bhaal.
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 \"Revere the ancestors, obey your king, bear yours arms with pride, fear no foe, hate the Greenskin, mistrust the Elf, and you can do no wrong.\" - An Old Dwarf Saying
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