You may be trying the wrong door. Ghaals key opens a previously locked door that's straight down the hall and to the west, when you first enter the level. There is a purple 'secret' door which you may be referring to which is actually an exit door for later on in the quest. You need to go down the staircase past the purple door. Have you spoken to the old man near the tomb yet? If so go down the stairs.
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