I play the game straight single player, no cheats, and like to lead. For this reason, I always play a Paladin/Human. I get good prices, good reaction, use some of the best gear in the game, kick the crap out of mages, undead, demons, etc. I use the rest of the party to fill out those necessary magic/cleric/thieving requirements. I am convinced this is the best single player approach for my still of play.
For my 2nd game, I will likely try a smaller party (maybe 2 or 3 PCs) by starting a multiplayer and converting to single and not use the NPCs for much of anything. I am still trying to decide what will work best for this approach.
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