Thanks Bokken, Finally succeeded with a full uninstall/re-install as suggested by the guys at Bioware. Had to trace an old registry entry from a previous install when the CDROM was still D: drive and manually remove. Start-up now recognizes the correct drive.
Now got a prob with Gamespy not launching the game for on-line play! Guess I'll just have to finish the game solo and then sort THAT out. PC's - you gotta love 'em.
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