In order to do the Planar Sphere quest you'll have to travel to the Umar Hills and get Valygar. You can't go to the Umar Hills until you get the "Murder in the Umar Hills" quest from some little kid in the slums.
As for the note from Ployer, it basically serves to flesh out the story behind a particular quest but isn't necessary to hold on to it. If you have Jaheria in your party then remembering where you got the note will be helpful (but not necessary). If you don't have Jaheira in your party then it's a non-issue.
FYI, if you find items and aren't sure if you should hold on to them you can always store them in a box or barrel until such time as you realize that you do or don't need them. Most items will state in the item description whether or not you need to use them for a particular quest that you're on. There are only a few things (mostly keys if I remember correctly) that don't.
Drink up.
-Tipsy
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