Those are fixed mobs.
The real trick in there with running in combat is to get to the spiral stairs and get the stuff off them before you actually engage the mobs in there. You can also start your fight from right under the stairs.
Another strategy is to push the combat button while you're still just out of line-of-sight (stand next to the entry), which gets you a free round in which you can:
Cast Soul/Element Shield and maybe Haste. Select those spells, and walk out to where at least one of the mobs can see you and press return (or the x on the end of the move bar). Next round, cast Eye For An Eye and Haste (or Super your tanks) and walk back behind the doorway, so they have to come to you. Usually Eye4Eye (potion or Locket if you can't cast at PL4) will kill the Cultists and their summonees when the Death Lords cast Death Wish. There are a few other strategies that work here; one is to run as soon as at least most of the Cultists are dead. You might end up having to fight one of the Death Lords and/or the Sorceress Queen on the way, but if you get down the path quickly, you'll have only one of them.
Another strtegy is to engage the 3 Siges outside and drag them up to the entry and then cast all your buffs in as many rounds as you need--then step into view of the other mobs...
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