Yes the instakill of fang is IMO more preferable.
That extra swing is draining your stamina, wheras the effect of the instakill is (among other things) typically reducing the stamina expenditure.
As far which weapon will end your opponents life more quickly - averaged out, I'd think they were pretty close (depending on the opponent and its level).
Of course if you have someone casting haste then its a no-brainer, go for fang.
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