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I tend to use males as my 'Tanks' and females as my main casters, bards, gadgeteers etc. I mostly do that as you get that stamina pendent in Arnika, useful for females.
Differences between the sexes can be a good thing, different ways to develop your party, you can run the same classes in 2 different games and develop them totally separately, makes it more interesting. Unlocking powerstrike or reflection 2 or 3 levels sooner would make a big difference.
Just my 2 pence worth.