It pays to check the enemy's resistances, too. As soon as you have Mythology high enough, right-clicking on the enemy has a lot more info. High air resistance makes Asphyxiate less likely to succeed, etc. I've made a lot of stuff go away with Quicksand, Death Wish and Death Cloud.
I think gadgets and instruments succeed more because enemy resistance isn't factored into the odds. Caster level vs enemy level is also important.
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