"Remove Curse" is a fourth level mage or priest spell. Bishops also have the ability to remove curses as one of their special class abilities (it's the button marked with a cross). Other than that, though, you'd have to find or buy a scroll of remove curse... As far as I know, no NPC can remove curses for you.
By the way, don't assume that simply because something is cursed it's a bad item... Many of the best weapons in the game (including Bloodlust) are cursed.
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