Well, I can give you some advice that was given me. First of all, especially when designing quests, is to write EVERYTHING down. maybe even plot and plan it out on paper. And from the days of FRUA, the advice is to start small... I mean sure everyone wants to make a "Save the world/multiverse" epic 4 year game with thousands of different endings depending on who you talked to/ attacked/ joined with, but its much easier to do a small adventure or set of adventures than that, and then you'll have a bit of experience to build on.
As for the FRUA newsletters, they are full of advice and can be found at
http://www.frua.dns2go.com/pc/uanews/
SilentThief