Could you give us some information on magic items, level and intended enemy?
For example, in a world with almost no magic items, it pays to concentrate on casting ability. In a world where you can be immune to everything and the kitchen sink through items, that becomes far less important. You'd fight another player's rogue character utterly differently from how you would an NPC skeletal wizard. At level 5, your priorities are much different from level 40. Fighting a group of enemies is not the same as fighting a single one. These and other things do matter when determining the 'best' build.
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