I have the same sound setup that you do.
Do you have the latest drivers downloaded from Creative Labs?
If not, then start there.
I was having the exact same problem...but not just with NWN...it happened with IWDII as well. After I installed the latest drivers last week, I have not had the problem to reoccur.
I am running WinXP. The reason I only installed the drivers as of last week was because I forgot to when I upgraded my OS...
If that does not work...then let me know. I will try to research it with you. Eventually, (Meaning when I get the $$$) I will be buying an Audigy 2. I think Live! is getting too outdated, and the Audigy 2 supports THX!
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