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Maybe.
From my understanding, items will have a point value, based upon their powers.
Characters can be of 3 types... world specific (a single place), vault (usuable on various servers), and client local.
Now, to play in a world specific type place, you'd probably need the item approved by the powers in charge there... if they even let you import a character (unlikely, if that is their set-up). For the vault, the vault limits how much xp/loot you can get in an adventure. If the item is deemed too powerful for your character... it won't check in. And as for the one on your machine, it's the GM choice if he wants to let you use it or not.
In any case, you can save a vault character locally before checking him/her back into the vault... so you can have two versions of the same character.
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