Well, dunno if it's caused by raiding his cabinet. I did that once (was uninpressed by the items), and he never attacked us. Of course, I had my rogue do the dirty work before Nikky woke up. It may be different if you try this when he's up and about.
As to being "central to the plot", the game lies. I've had several parties that never even entered his room, so we never agreed to the favor, and the game progressed as usual. The only difference is, when we went to the Fields of Slaughter, we really went there instead of being kidnapped by Nikky. Of course, we missed out on the "share wisdom" xp, but it was a small price to pay to avoid the silly demon hunt.
Nightowl2
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