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Whatever you do do not engage her in the room you find her, its full of traps and she casts a cloudkill early on. She has very high magic resistance so you can't rely on spells. If you have any mages use them to take out the Yuan-ti with her.
Best tactic I found was to setup a position in the corridor outside the room and lure them out. Haste everybody to maximise attacks and hit her as hard as you can. Mop up the Yuan-ti only when she is dead.
Good luck.
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Listen, strange ladies lying in ponds distributing swords is no basis for a system of government. Supreme executive power comes from a mandate from the masses, not some farcical aquatic ceremony.
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