Definitely alter your party as to alignment, as some of the best items in the game can't be used by "good" members. I was glad I brought a couple of "Neutrals" along for that! Also, there are items that can't be used by Chaotics, or Lawfuls as well. The only type of alignment I don't use is "evil" (Good/Neutral here), but the rest of my characters run the gamut from my Lawful Good Paladin to my Chaotic Neutral Thief (I can just imagine the banter between THOSE two!)
Cheers,
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I know who you are...I saw what you did!