The shattered tower in the Severed Hand had many artifacts in it years ago, but they were all detonated when the Horde overran the Seldarine. That tower is now only rubble and is inaccessible.
The Arboretum caretaker (who is alive, by the way) never ceases asking for more items to put into the Arboretum. The only quest-related items are the water, seeds, squirrels, and birds. Although you can't do this in the game, if you could chip some frozen fish out from the Museum of Dugmaren, thaw them, and put them into the water *that* would be an interesting notion.
Unfortunately, Nym's "stash" doesn't exist in the game, either.
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