You don't need the Symbol of Myrkul anymore. You have to be carrying it to open a certain door in Kresselack's Tomb, where you found it in chapter 1. It has no other use.
I don't know what else you have, but in general you can leave stuff you think you might need later in a container somewhere. I use a container upstairs in the inn in Kuldahar and one in Severed Hand. Those are areas with shops, so they're places I return to every once in a while anyway.
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