In straight BG1, there is only one 5th-level Wizard spell: Cloudkill. It CANNOT be cast from memory (even if you're soloing), unless you remove the EXP cap. You can, however, cast it from a scroll--and there are 2 scrolls of it in the game.
With ToSC installed, a pure Wizard can reach Level 9, allowing him to cast 1 Level 5 spell per day, and there are a few new Level 5 spells available--but, sadly, Lower Magic Resistance is not one of them.
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Volothamp's Comeuppance
Everything you ever needed to know about the entire Baldur's Gate series......except spoilers.
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