I would not recommend doing the
Cult of the Unseeing Eye quest until your party has levelled up a fair bit. It is, to put it mildly,
extremely perilous to new players.
Without spoiling too much, there is a point in this quest where there is no point of return until you finish it. If, and when, you do finally start this quest, remember to
make a savegame first.
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Additionally, when exploring the unmarked houses in the main city, you will encounter some doors that are trapped.
These doors are trapped for a reason. It is the game's universal language of, "Are you sure you want to enter here?"
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De'Arnise Keep and Tradesmeet are fairly newbie-friendly quests. Unless you installed mods, then all bets are off.
Umar Hills is not so newbie-friendly, but not that hard either.
Windspear Hills is moderately difficult, or to put it another way, challenging.
Cheers.