Well, to aid my Solo quest I made myself an item. A hood which doesn't allow the things that end game in Solo. IIRC Charm Person, Dire Charm, Hold, Imprisonment, etc. Just to save me from reloading.
If that is too cheesey for some people, tough, it's my first solo run so I think you can cut me some slack
(Its in the form of a Cowl, the Cowl of Mind Protection IIRC)
The picture was taken from the Thieves Cowl item in ToB.