Yeah Micah, I would cover stuff many others overlook or just don't cover--like you said, the small things.. the game options, does it have keyboard shortcuts that can be reconfigured, video and audio features etc..
And also cover the basics of the gameplay--magic system, inventory system and other things you said are great! (wrote them down). (I agree, others will cover the boss battles, but I would just give some quick tips on how to help them win.
I LOVE watching the Lets Play by NecroScope.. he's funny as hell sometimes, and just did a lets play on StoneKeep.. That old ass game--I didn't really like it and never finished it, so watching it was fun, yet geez.. boring. lol seemed like every level looked the same forever.
But yeah, should be good.. Anyone know a good HD webcam? I would use my headset for the mic.. want it to be at least 1080p so you can see the games in clear crisp video.
The worst thing about some reviewed games is when they're in 480 and blurry as hell

but I deal with it..