What level are you? If you're doin' the Haer'Dalis quest, you may want to lay off there a bit. Have you rescued Imoen? If you have, after you return is the time to go get those guys. There's no reason to go there before then: you're gonna get eaten up. Optimally, though, if you're really looking to take them out, use chaotic commands, and then try to get them with area effect spells, after some lower resistances. I'd say hold off though.
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