I believe - but don't quote me on this, it's a long time since I've played BG1 - that both of those adults were guilty of frightening the children. At least I distinctly remember killing them both in every run through the game, although the exact reason I had for this escapes me at the moment.
As for that other twin, don't know where he/she could have gone. Try checking all the little angles of the house, sometimes they're behind a door and the 'fog of war' will then only reveal them if you stand in the exact correct spot.
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