Imp Irenicus is my only mod so far that was explicitly designed with a "balanced party" in mind. Thus it's one of the few places in the game where you will actually feel some pain for being a solo character (normally it is actually pretty much an advantage if you know what you're doing).
You could certainly do it without Time Stop -- a mage with vecna, power, alacrity and a pro-mw scroll doesn't really need to worry about the monsters trying to get a hit or two in while she casts a bunch of spells. Heck, you can even do it without ToB HLAs (someone reported such a success).
A pure fighter would be tough, mostly because of Greed. Wand of Magic Missiles, Book of Infinite Spells (?), ... but the only "easy" way I can see to do it is to cheesily drop Sanchu on the floor before the fight starts.
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