what do i do with the vampires that are threatening to attack me??

1) Kill them.

2) Stay inside at night.

3) Run away from Athkatla -- there are many adventures outside the city.

-- Nifft

My vote is to kill them there are plenty of temples around for restoration if your priest cant cast it yet

Yea, you get some good XP for cleaning them up.
If you've got trouble with them, post some stats of your party (which NPCs you use, at what level, etc.) and we can give you some tips.

Thank ya guys. i can take those vampires

Make sure your party includes a cleric who can cast such spells as False Dawn. With that, and the upgraded Mace of Disruption, you shouldn't have too much trouble.

And make sure you have the licence for magic if you're planning to cast spells, otherwise the Cowled Wizards will attack you. When I fought the vampires for the first time I was surprise how there could be only 4 of them at first, and then all of a sudden 3 more wizards. :D