Yo people, I got me a problem with a bunch of pansy looking ice mysts and a golem in the 2nd level of watchers keep. Nothing I can do hurts them, and I mean I have my fair share of powerful spells and weapons. What's going on 'ere?? Can anyone help me out please???

I think if you follow what those notes you find in the various libraries it should help. IIRC, if you turn the fan on full, and open the doors between the air and poison labs, and the poison and ice labs, the poison mist should go into the ice lab and make them vulnerable.