So im a priest of talos and I went to the temple district to listen to all the babble about the unseeing eye and some priest of talos asked me to come and talk to him, but every time I try to enter my game shuts down. I have palyed throug the game several times(never as a cleric before) and this has never happend.
I have the latest patch and the dungeon be gone mod installed...

There's probably something in the Temple of Talos that starts a conflict with the game engine or something.

Have you tried an earlier save yet?

Yes and its not only the tempel of talos its al the temples at the temple district, the sewers work fine how ever, and i tried to re-install it to did not work either..