I just started a new game and have made it to the Copper Coronet. Once inside, everyone I click on to talk to "appears busy". I can't talk to anyone. I reloaded once and that allowed me to talk to the barkeep and Lord Jierdan. I reloaded again and I was back to zero, no one would talk to me. Can anyone tell me how to fix this?

Are you fully patched?
I mean, Have you downloaded the official patch and installed it yet?
If not, then do so.

Probably most widespread bug there is. Patch your game with the official patch and the Baldurdash Fixpack. Links in the FAQ thread. ;)

Thanks fellas, seems to be working now.